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KMID : 0374019930160030227
Ewha Medical Journal
1993 Volume.16 No. 3 p.227 ~ p.234
A Clinical Study on Signet Ring Cell Type of Gastric Adenocarcinoma



Abstract
In the past, gastric carcinomas composed preddominantly of signet ring cells formed only a small percentage of gastric malignancies. However, we have had the impression that in rece?? yars the relative incidence and amount of signet ring cells in
biopsy
and resection specimens of gastric carcinoma have risen sharply. This report is an analysis of 69 cases of signet ring cell type of gastric adenocarcinoma diagnosed at Ewha Womens University Hospital from January, 1987 to December, 1991 The
results
obtained were summerized as follows.
1) The male to female ratio was 1 : 12
2) The peak age incidence was the 6th decade and the 7th decade with 23.9% each other. and the 8th decade with 17.4%, the 5th decade and the 4th decade with 16% each other Average age of patients was younger than entire than entire gastric
adenocarcinoma.
3) the major clinical symptom was epigastric pain, indigestion, vomiting and abdominal fullness in decreasing orders.
4) The macroscopic feature of the signet ring cell type of adenocarcinoma by gastrofiberscopy showed Borrmann's type III 26 cases (37.6%), type IV 21 cases (30.4%). type II 10 cases (14.5%).
5) The location of signet ring cell type was mainly the gastric antrum 39cases (56.5%). the body cases (26%), and widespread from body to antrum 9 cases (13%).
6) the size of lesion showed above 3cm with 53% 1.5~3.0cm with 31.3%m, below 1.5cm with 15.7% in frequency.
7) Thirty out of 39 cases (76.9%) involve to the serosa, 3 cases (7.7%) to the muscle layer, 3 cases (7.7%) to the mucosa and the submucosa each other.
8) Distant metastases were relatively frequently occurred in increased increased CEA group.
9) Five-year survival rate of 49 cases was 62.8%.
KEYWORD
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